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SCIENCE CHINA Materials, Volume 63 , Issue 9 : 1808-1817(2020) https://doi.org/10.1007/s40843-020-1339-8

Facile thermal decomposition synthesis of sub-5 nm nanodots with long-lived luminescence for autofluorescence-free bioimaging

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  • ReceivedJan 7, 2020
  • AcceptedApr 8, 2020
  • PublishedMay 27, 2020

Abstract


Funding

the National Natural Science Foundation of China(21925401,21904100)


Acknowledgment

This work was supported by the National Natural Science Foundation of China (21925401 and 21904100).


Interest statement

The authors declare that they have no conflict of interest.


Contributions statement

Yuan Q and Wang J proposed the research direction and guided the project. Lv X and Chen N designed and conducted the experiments. Lv X wrote the paper with the support from Yuan Q, Wang J and Chen N. All the authors checked the manuscript.


Author information

Xiaobo Lv obtained his BSc degree from Northeast Forestry University in 2017. He is currently pursuing his Master degree in Prof. Quan Yuan’s group at Wuhan University. His interests focus on the controlled synthesis of persistent luminescence nanomaterials and exploring their potential biomedical applications.


Na Chen obtained her BSc and MSc degrees from Hunan University. Later, she joined Prof. Quan Yuan’s group at Wuhan University. Currently, she is a PhD candidate in Wuhan University. Her research interest focuses on the controlled synthesis of luminescent nanomaterials for biomedical applications.


Jie Wang obtained his BSc degree from Wuhan Institute of Technology. He obtained his PhD degree in Prof. Quan Yuan’s group at Wuhan University. Now he is a postdoctoral fellow in Wuhan University. His research focuses on designing functional luminescence materials for biosensing and bioimaging.


Quan Yuan obtained her PhD degree from Peking University in 2009. Later, she continued her postdoctoral research at the University of Florida. In 2012, she joined Wuhan University as a full professor. Her research focuses on the controlled synthesis of functional nanomaterials and exploring their biomedical applications.


Supplementary data

Supplementary information

Supporting data are available in the online version of the paper.


References

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  • Scheme 1

    Schematic illustration of the synthesis of PLNDs via a thermal decomposition method.

  • Figure 1

    (a) TEM and HRTEM (inset) images of the ZGO:Cr PLNDs. (b) The size distribution of the ZGO:Cr PLNDs. (c) XRD pattern and (d) EDS analysis of the ZGO:Cr PLNDs. (e) Phosphorescence spectrum and (f) persistent luminescence decay images of the ZGO:Cr PLNDs.

  • Figure 2

    (a) TEM image, (b) size distribution, (c) phosphorescence spectra, and (d) persistent luminescence decay images of the ZGO:Al,Cr PLNDs. (e) TEM image, (f) size distribution, (g) phosphorescence spectra, and (h) persistent luminescence decay images of the ZGO:Sc,Cr PLNDs.

  • Figure 3

    (a) TEM image and size distribution, (b) phosphorescence spectrum and (c) persistent luminescence delay images of the ZnS:Cr PLNDs.(d) TEM image and size distribution, (e) phosphorescence spectrum and (f) persistent luminescence delay images of the CaF2 PLNDs.

  • Figure 4

    (a) Schematic illustration for the construction of the liposome@ZGO:Al,Cr. (b) Confocal microscopy images of the liposome@ZGO:Al,Cr. (c) AFM image, (d) height profile analysis and (e) persistent luminescence decay images of the liposome@ZGO:Al,Cr. (f) Persistent luminescence decay images of the pork tissue injected with the liposome@ZGO:Al,Cr. (g) Photograph of the pork tissue injected with the liposome@ZGO:Al,Cr.

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