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Encapsulation of live cells by metal-organic frameworks for viability protection

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  • ReceivedNov 29, 2018
  • AcceptedDec 14, 2018
  • PublishedJan 18, 2019

Abstract


Funded by

the National Key Basic Research Program of China(2014CB931801,2016YFA0200700)

the National Natural Science Foundation of China(2189038,21721002,21475029)

Frontier Science Key Project of Chinese Academy of Sciences(QYZDJ-SSW-SLH038)

and K. C. Wong Education Foundation.


Acknowledgment

This work was supported by the National Key Basic Research Program of China (2014CB931801 and 2016YFA0200700), the National Natural Science Foundation of China (2189038, 21721002 and 21475029), Frontier Science Key Project of Chinese Academy of Sciences (QYZDJ-SSW-SLH038), and K. C. Wong Education Foundation.


Interest statement

The authors declare that they have no conflict of interest.


Contributions statement

Sun C and Chang L conceived the idea, proposed the strategy, designed and performed the experiments, analyzed the results and wrote the manuscript. Hou K helped writing and modifying the manuscript. Liu S and Tang Z supervised the project, helped design of experiments, evaluated the data and wrote the manuscript.


Author information

Chao Sun received his MSc degree in 2011 from Xinjiang University. Then he joined Tang’s group at Harbin Institute of Technology in 2012. He is now a PhD student and his research interest focuses on the synthesis and applications of porous materials.


Lin Chang received her MSc degree in 2010 from Beijing University of Technology. Then she joined National Center for Nanoscience and Technology as an assistant engineer (2011–2014). Now she is an engineer and her research focuses on the synthesis and characterization of nanomaterials.


Zhiyong Tang obtained his PhD degree from the Chinese Academy of Sciences in 2000 under the direction of Professor Erkang Wang. After finishing his postdoctoral training at the Swiss Federal Institute of Technology, Zurich, and the Universtiy of Michigan, he returned to China and took a professor position at the end of 2006. His main research interest is focused on the preparation, assembly and applications of functional inorganic nanomaterials.


Supplement

Supplementary information

Supplementary data are available in the online version of the paper.


References

[1] Wang B, Liu P, Tang R. Cellular shellization: surface engineering gives cells an exterior. BioEssays, 2010, 32: 698-708 CrossRef PubMed Google Scholar

[2] Léonard A, Dandoy P, Danloy E, et al. Whole-cell based hybrid materials for green energy production, environmental remediation and smart cell-therapy. Chem Soc Rev, 2011, 40: 860-885 CrossRef PubMed Google Scholar

[3] Wang G, Li X, Mo L, et al. Eggshell-inspired biomineralization generates vaccines that do not require refrigeration. Angew Chem, 2012, 124: 10728-10731 CrossRef Google Scholar

[4] Yang SH, Ko EH, Jung YH, et al. Bioinspired functionalization of silica-encapsulated yeast cells. Angew Chem, 2011, 123: 6239-6242 CrossRef Google Scholar

[5] Yang SH, Lee KB, Kong B, et al. Biomimetic encapsulation of individual cells with silica. Angew Chem Int Ed, 2009, 48: 9160-9163 CrossRef PubMed Google Scholar

[6] Park JH, Hong D, Lee J, et al. Cell-in-shell hybrids: chemical nanoencapsulation of individual cells. Acc Chem Res, 2016, 49: 792-800 CrossRef PubMed Google Scholar

[7] Li S, Dharmarwardana M, Welch RP, et al. Template-directed synthesis of porous and protective core-shell bionanoparticles. Angew Chem Int Ed, 2016, 55: 10691-10696 CrossRef PubMed Google Scholar

[8] Krol S, del Guerra S, Grupillo M, et al. Multilayer nanoencapsulation. New approach for immune protection of human pancreatic islets. Nano Lett, 2006, 6: 1933-1939 CrossRef PubMed ADS Google Scholar

[9] Lee J, Choi J, Park JH, et al. Cytoprotective silica coating of individual mammalian cells through bioinspired silicification. Angew Chem Int Ed, 2014, 53: 8056-8059 CrossRef PubMed Google Scholar

[10] Kempaiah R, Salgado S, Chung WL, et al. Graphene as membrane for encapsulation of yeast cells: protective and electrically conducting. Chem Commun, 2011, 47: 11480-11482 CrossRef PubMed Google Scholar

[11] Wang B, Liu P, Jiang W, et al. Yeast cells with an artificial mineral shell: protection and modification of living cells by biomimetic mineralization. Angew Chem Int Ed, 2008, 47: 3560-3564 CrossRef PubMed Google Scholar

[12] Fakhrullin RF, Minullina RT. Hybrid cellular−inorganic core−shell microparticles: encapsulation of individual living cells in calcium carbonate microshells. Langmuir, 2009, 25: 6617-6621 CrossRef PubMed Google Scholar

[13] Ko EH, Yoon Y, Park JH, et al. Bioinspired, cytocompatible mineralization of silica-titania composites: thermoprotective nanoshell formation for individual Chlorella cells. Angew Chem Int Ed, 2013, 52: 12279-12282 CrossRef PubMed Google Scholar

[14] Konnova SA, Sharipova IR, Demina TA, et al. Biomimetic cell-mediated three-dimensional assembly of halloysite nanotubes. Chem Commun, 2013, 49: 4208-4210 CrossRef PubMed Google Scholar

[15] Kuo WS, Wu CM, Yang ZS, et al. Biocompatible bacteria@Au composites for application in the photothermal destruction of cancer cells. Chem Commun, 2008, 45: 4430 CrossRef PubMed Google Scholar

[16] Furukawa H, Cordova KE, O'Keeffe M, et al. The chemistry and applications of metal-organic frameworks. Science, 2013, 341: 1230444 CrossRef PubMed Google Scholar

[17] Saliba D, Ammar M, Rammal M, et al. Crystal growth of ZIF-8, ZIF-67, and their mixed-metal derivatives. J Am Chem Soc, 2018, 140: 1812-1823 CrossRef PubMed Google Scholar

[18] Zhuang JL, Ceglarek D, Pethuraj S, et al. Rapid room-temperature synthesis of metal-organic framework HKUST-1 crystals in bulk and as oriented and patterned thin films. Adv Funct Mater, 2011, 21: 1442-1447 CrossRef Google Scholar

[19] Wang Z, Hu S, Yang J, et al. Nanoscale Zr-based MOFs with tailorable size and introduced mesopore for protein delivery. Adv Funct Mater, 2018, 28: 1707356 CrossRef Google Scholar

[20] Qin JS, Yuan S, Lollar C, et al. Stable metal–organic frameworks as a host platform for catalysis and biomimetics. Chem Commun, 2018, 54: 4231-4249 CrossRef PubMed Google Scholar

[21] Wang C, Liu X, Keser Demir N, et al. Applications of water stable metal–organic frameworks. Chem Soc Rev, 2016, 45: 5107-5134 CrossRef PubMed Google Scholar

[22] Zhao M, Yuan K, Wang Y, et al. Metal–organic frameworks as selectivity regulators for hydrogenation reactions. Nature, 2016, 539: 76-80 CrossRef PubMed ADS Google Scholar

[23] Zhao M, Deng K, He L, et al. Core–shell palladium nanoparticle@metal–organic frameworks as multifunctional catalysts for cascade reactions. J Am Chem Soc, 2014, 136: 1738-1741 CrossRef PubMed Google Scholar

[24] Cai Y, Wu Y, Xuan T, et al. Core–shell Au@metal–organic frameworks for promoting raman detection sensitivity of methenamine. ACS Appl Mater Interfaces, 2018, 10: 15412-15417 CrossRef Google Scholar

[25] Wu X, Xiong S, Mao Z, et al. A designed ZnO@ZIF-8 core-shell nanorod film as a gas sensor with excellent selectivity for H2 over CO. Chem Eur J, 2017, 23: 7969-7975 CrossRef PubMed Google Scholar

[26] Zhan G, Fan L, Zhou S, et al. Fabrication of integrated Cu2O@HKUST-1@Au nanocatalysts via galvanic replacements toward alcohols oxidation application. ACS Appl Mater Interfaces, 2018, 10: 35234-35243 CrossRef Google Scholar

[27] Zhang D, Zhou W, Liu Q, et al. CH3NH3PbBr3 perovskite nanocrystals encapsulated in lanthanide metal–organic frameworks as a photoluminescence converter for anti-counterfeiting. ACS Appl Mater Interfaces, 2018, 10: 27875-27884 CrossRef Google Scholar

[28] Luo F, Lin Y, Zheng L, et al. Encapsulation of hemin in metal–organic frameworks for catalyzing the chemiluminescence reaction of the H2O2–luminol system and detecting glucose in the neutral condition. ACS Appl Mater Interfaces, 2015, 7: 11322-11329 CrossRef Google Scholar

[29] Liu G, Xu Y, Han Y, et al. Immobilization of lysozyme proteins on a hierarchical zeolitic imidazolate framework (ZIF-8). Dalton Trans, 2017, 46: 2114-2121 CrossRef PubMed Google Scholar

[30] Doonan C, Riccò R, Liang K, et al. Metal–organic frameworks at the biointerface: synthetic strategies and applications. Acc Chem Res, 2017, 50: 1423-1432 CrossRef PubMed Google Scholar

[31] Li P, Moon SY, Guelta MA, et al. Encapsulation of a nerve agent detoxifying enzyme by a mesoporous zirconium metal–organic framework engenders thermal and long-term stability. J Am Chem Soc, 2016, 138: 8052-8055 CrossRef PubMed Google Scholar

[32] Lian X, Erazo-Oliveras A, Pellois JP, et al. High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks. Nat Commun, 2017, 8: 2075 CrossRef PubMed ADS Google Scholar

[33] Chen WH, Vázquez-González M, Zoabi A, et al. Biocatalytic cascades driven by enzymes encapsulated in metal–organic framework nanoparticles. Nat Catal, 2018, 1: 689-695 CrossRef Google Scholar

[34] Mehta J, Bhardwaj N, Bhardwaj SK, et al. Recent advances in enzyme immobilization techniques: Metal-organic frameworks as novel substrates. Coord Chem Rev, 2016, 322: 30-40 CrossRef Google Scholar

[35] Tsumori N, Chen L, Wang Q, et al. Quasi-MOF: exposing inorganic nodes to guest metal nanoparticles for drastically enhanced catalytic activity. Chem, 2018, 4: 845-856 CrossRef Google Scholar

[36] Lian X, Fang Y, Joseph E, et al. Enzyme–MOF (metal–organic framework) composites. Chem Soc Rev, 2017, 46: 3386-3401 CrossRef PubMed Google Scholar

[37] Liang K, Richardson JJ, Doonan CJ, et al. An enzyme-coated metal-organic framework shell for synthetically adaptive cell survival. Angew Chem Int Ed, 2017, 56: 8510-8515 CrossRef PubMed Google Scholar

[38] Liang K, Richardson JJ, Cui J, et al. Metal-organic framework coatings as cytoprotective exoskeletons for living cells. Adv Mater, 2016, 28: 7910-7914 CrossRef PubMed Google Scholar

[39] Blackwell KJ, Singleton I, Tobin JM. Metal cation uptake by yeast: a review. Appl Microbiol Biotechnol, 1995, 43: 579-584 CrossRef Google Scholar

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