Wound infections caused by quick emergence of drug-resistant bacteria pose a challenge globally. Professor Runhui Liu and co-workers designed an antibiotic-free antibacterial hydrogel by loading the host defense peptide-mimicking peptide polymer into the biocompatible and biodegradable hyaluronic acid hydrogel, which showed potent activity against methicillin-resistant Staphylococcus aureus (MRSA) in vitro and promising effectiveness in treating MRSA-infected wounds in vivo. This study suggests a facile and effective strategy to construct antibacterial hydrogels that enable efficient healing of MRSA-infected wounds (see the article on pages 1824-1833).

Wound infections caused by quick emergence of drug-resistant bacteria pose a challenge globally. Professor Runhui Liu and co-workers designed an antibiotic-free antibacterial hydrogel by loading the host defense peptide-mimicking peptide polymer into the biocompatible and biodegradable hyaluronic acid hydrogel, which showed potent activity against methicillin-resistant Staphylococcus aureus (MRSA) in vitro and promising effectiveness in treating MRSA-infected wounds in vivo. This study suggests a facile and effective strategy to construct antibacterial hydrogels that enable efficient healing of MRSA-infected wounds (see the article on pages 1824-1833).