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SCIENCE CHINA Life Sciences, https://doi.org/10.1007/s11427-021-2014-4

Neutrophil ferroptotic death promotes autoimmune pathogenesis

Zijian Pan 1,2,3,4,†, Nathchar Naowarojna 1,2,3,†, Yuqi Wang 1,2,3, Mangze Hu 1,2,3, Yilong Zou 1,2,3,*
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  • ReceivedSep 8, 2021
  • AcceptedSep 27, 2021
  • PublishedOct 27, 2021

Abstract

There is no abstract available for this article.


Funding

the Westlake Education Foundation and the Westlake Laboratory of Life Sciences and Biomedicine.


Acknowledgment

This work was supported by the Westlake Education Foundation and the Westlake Laboratory of Life Sciences and Biomedicine.


Interest statement

The author(s) declare that they have no conflict of interest. Yilong Zou is a consultant of Keen Therapeutics.


References

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[6] Yao Y., Chen Z., Zhang H., Chen C., Zeng M., Yunis J., Wei Y., Wan Y., Wang N., Zhou M., et al. Selenium-GPX4 axis protects follicular helper T cells from ferroptosis. Nat Immunol, 2021, 221127-1139 CrossRef PubMed Google Scholar

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  • Figure 1

    Neutrophil ferroptosis induced by IgG and IFN-α contributes to systemic lupus erythematosus (created with BioRender.com). GPX4, glutathione peroxidase 4; PL, polyunsaturated phospholipid.

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